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Sciences > Medical Science (Other) Hormonal regulation of sodium ions in the body

Patient 1 and 2 have the same plasma sodium concentration of 140mmol/L.  Patient 1 has an urine sodium concentration of 60 mmol/L. Patient 2 has an urine sodium concentration of 200 mmol/L. How can the plasma sodium concentration can be identical in these two patients, yet the urine sodium concentrations can be different.  This is due to the ability of the kidney to produce very dilute or very concentrated urine. As the filtrate goes up the ascending limb toward the CCD, it becomes extremely hypovolemic, due to the active sodium potassium pump pumping sodium out of the filtr...

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