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Sciences > Ecology & Environment Perchlorate: Environmental contaminate?: 1 of 1

Cabbage diets fed to rabbits by Chesney and his collegues in 1928, had a goitrogenic (suppression of thyroid function) effect due to the presence of cyanide in their leaves. Potassium thiocyanate administered to rats by Vanderlaan and Vanderlaan, caused discharge of iodide from the thyroid glands and prevented the accumulation of iodide in the gland. Five years later, Wyngaarden and his group, showed that potassium perchlorate also behaves like the potassium thiocyanate, although, it is more potent. Since then perchlorate has been extensively used in several studies as an antithyroid agent...
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