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Health & Fitness > Allergies How antihistamines work

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Antihistamines work by targeting receptor sites in the airways, blood vessels, skin and nose to prevent or block the release of histamine, a chemical released at the receptor site when an allergic reaction is occurring. Histamine is naturally produced by the body to fight off foreign agents, however, in some individuals the receptor sites become over stimulated and release an excess of histamine. This excess histamine can irritate the nose and eyes causing hay fever symptoms such as sneezing and itchy and watery eyes and nose. An antihistamine's mechanism of action is to coat the allerge...

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