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Animal experimentation. This subject is a source of great controversy. Personally, I hate seeing some of what happens in the research laboratory. However, scientist that I am, I recognize the need for some way to test new products and drugs. Only two ways exist: in vivo (animal research) and in vitro ("in glass", that is outside the body, in a test tube, for example). Each has advantages as well as serious limitations.

Good in vitro systems do exist. The obvious limitation being that isolated cells or tissues can never simulate the complex interactions occurring in an animal. These alternatives do have their uses. They can give preliminary information to refine later tests in animals. This can reduce the number of animals needed. It may also reduce possible suffering by predicting cellular toxicity, allowing researchers to better target dose levels.

Without animal experiments, the drugs we all rely on would not exist. As such, the lab animal is one of our most important resources for maintaining our well-being. Despite some serious limitations of animal-based studies, there simply is no alternative to the lab animal at this time.

Contrary to many claims, laboratory animals are not abused. Yes, there were many questionable practices in the past. Both lawmakers and researchers responded by creating new rules for the use of animals. Today, any lab using research animals must pass inspections and follow regulations regarding treatment of the animals. Also, many animal research facilities comply with the voluntary program of the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC at http://www.aaalac.org). Labs participating in AALAC's voluntary accreditation process prove that they meet the minimum standards required by law, as well as going the extra mile to achieve excellence in animal care and use.

There are those opponents who claim that animal models cannot predict human response. This is not entirely true, but there are many diseases where no suitable animal model exists. This lack of suitable models is probably the most serious limitation to animal research. Where good models exist, animals are an invaluable resource for researchers. Where suitable models do not exist, we must not blindly squander the lives of more animals. We should work toward finding better models.

So in summary: Yes the use of animals in experiments is acceptable. However, in using animals we should always be aware that these are living creatures. We are responsible for their well-being as they help us to protect our own well-being.

Learn more about this author, Melissa J Luther.
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