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of the tissues in this case the penis which make it impossible for an erection to occur. Tadalafil inserts sildenatil which relaxes the blood vessels in the penile wall and allows for an erection. Ok, so how does an original erection occur? Well pornography and thongs aside, medically an erection in a male occurs when the parasympathetic nervous system is aroused by tiny chemical impulses (usually in response to a thong on flesh or a pretty lady =0) , these impulses excite the body into literally having all the blood rush into the arterial wall of the penis, enlarging it and cause it to grow in size and vertical velocity. The Erection, otherwise known as a "hard-on". Why is it hard? Well the name comes from the blood vessels which surround the interior of the penis, when those vessels are full of blood, the entire penis becomes rigid. Like how if you fill a balloon with air you'll notice the balloon's surface becomes tighter and firmer, and bigger. This isn't magic people, its basic physiology. Your body is a Beautiful Machine. Once the PNS is activated, nitric oxide is released which then binds to receptors (compare to a tv antenna) of the enzyme guanylate cyclase. The cyclase then leads to increased levels of cyclic guanosine monophosphate (cGMP)-sounds cool huh like a bomb-which essentially relaxes the smooth muscle (called vasodilatation) lining found in the penile wall (called the corpus cavernosum), leading to a huge inflow of blood, and finally an Erection. Systematic like a clock. Pretty Beautiful.
There is an enzympe-phosphodiesterase type 5 (PDE5 as previously mentioned) which if overly high in amount within the male penis-degrades cGMP production and makes it impossible for the penis to relax to allow for an influx of blood flow. Tadalafil inhibits (blocks) this enzyme from being released, allowing nature's natural process of penile erection to proceed as the prophecy foresees. Tadalafil's chemical structure is very similar to that of cGMP, and it acts as a binding agent (think of a cop vs. a criminal) to provide competition to PDE5, (imagine the cop beating the criminal and arresting him/her). This fierce battle allows for further production of cGMP, making arousal although an assisted process, still natural. Tadalafil's process also helps to produce better erections overall in comparison to a normal male. (Just think, Tadalafil provides a double dose of extra strength to the penis). Tadalafil isn't some scary medicine that acts when unprovoked.
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