by Melanie Grimes

Created on: April 11, 2011   Last Updated: April 12, 2011

Phosphatidylserine  is a type of molecule found in every cell in the body. Made of  amino acids and fatty acid, these molecules are vital to life itself. Derived from lecithin found in soybeans, phosphatidylserine  was first isolated in 1942 from bovine cortex. phosphatidylserine is an important nutrient that acts as a building block for brain cells. While the modern diet may contain 150 mg a day of this nutrient, the daily recommendation is 600 mg per day. 

What does phosphatidylserine do?

Phosphatidylserine  works by enhancing glucose metabolism in the brain cells. This assists the neurotransmitters to speed information  in the brain. The chemical reaction of phosphatidylserine  helps grow new receptors on the cell membrane, thereby allowing for more information to be sent between brain cells. The neurotransmitter, acetylcholine is responsible for memory functions in the brain. phosphatidylserine rebuilds the supply of that important brain nutrient. phosphatidylserine  also makes choline more available to the cells, and also increases the dopamine, a substance known to aid in depression and mood.

Brain benefits from taking phosphatidylserine

With aging, the amount of actylcholine in the brain decreases, and this slows brain function. Adding phosphatidylserine to the diet increases memory, mood, and concentration. It inhibits stress by reducing the adrenal hormone, cortisol. phosphatidylserine has been shown to increase attention span and being studied for use with Attention Deficit Disorder, a condition that affects both the young and the older populations. phosphatidylserine can relieve symptoms of depression and boost mood, as well as increase brain focus and enhance the brain’s ability to store new data.

Other health benefits of phosphatidylserine

In addition to benefits in cognition and mood, phosphatidylserine has been shown to aid muscle building, speed recovery from overuse injuries, and reduce exercise-induced stress. This is accomplished by a reduction on cortisol levels.

Safety

The American Food and Drug Administration (FDA) has designated phosphatidylserine as Generally Recognized As Safe (GRAS) when taken in the recommended daily dose. This designation means that the product is considered safe by experts. The designation exempts phosphatidylserine  and other GRAS products from the usual FDA restrictions and requirements. It has been found to be compatible with most pharmaceutical drugs.

Recommended dosage of phosphatidylserine

The recommended dosage of phosphatidylserine is 200 mg taken three times a day. 

Food sources of phosphatidylserine

Phosphatidylserine is found in the greatest quantities in organ meats such as liver and kidneys. Mackerel contains a large amount as well, as does eel, tuna and soft-shell clams. White beans also contain a good amount of phosphatidylserine. Small amounts are found in dairy and in some vegetables.

Learn more about this author, Melanie Grimes.
Click here to send this author comments or questions.