by B. Iris Tanner

Created on: December 19, 2010   Last Updated: December 21, 2010

Vaccinating against the most common diseases is standard operating procedure for most cat owners. Ironically, though, it is possible for vaccinated cats to develop side effects that in some cases can be worse than the original disease. Consequently, it is very important to make an informed decision about the vaccines your cat is given and to monitor it for signs of trouble afterward.

The basic “three-way” vaccines that most kittens receive provide protection against two different types of respiratory disease (calici and rhinotracheitis) as well as panleukopenia, which used to be called distemper. Current vaccination protocols, which have changed significantly in the last five years, call for kittens to receive one set of vaccines prior to 9 weeks of age, a second set after 9 weeks, and a third set after 16 weeks. A rabies vaccine is usually given after 12 weeks.

Feline vaccines are generally available in two forms; “killed” and “modified live.” The killed vaccines, which include additives to stimulate a stronger immune response, may be more likely to spark side effects, as cats can become sensitive to these additives. The live or modified live vaccines are sometimes considered safer with regard to potential reactions. However, a cat vaccinated with live vaccine may shed the virus for several days after vaccination, which can be a problem in multiple cat households.

Cats and kittens often appear drowsy and uninterested in food or water for the first 24 hours following vaccination. This should not be a major cause of concern unless it extends beyond that initial 24-hour period.  Vets generally recommend that you feed an especially fragrant (i.e. fishy) food after vaccination and warm it in the microwave to make it smell even more enticing.  If your kitty doesn’t appear to be drinking much water within this period, it may be wise to dilute some chicken broth with water and offer it to the cat. Most will find the taste appealing and this can help prevent dehydration.

Fortunately, more serious reactions to the three-way vaccines are unusual. These are more likely to be associated with vaccination for rabies and/or feline leukemia. Cats may develop tenderness or lumps at the vaccination site or in rare cases, anaphylactic shock, which is a true medical emergency. Anaphylactic shock can occur within a few seconds of vaccination or as long as 24 hours afterward. Signs can include vomiting or diarrhea, rapid heart

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