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Triclosan: Uses and effects

Triclosan: Is it for you?

Triclosan is an active ingredient present in some toothpastes, notably
Colgate Total. Claims of up to 30% reduction in gingivitis (gum disease)
and plaque formation are given for it. There are also many associated health
concerns, some so severe that triclosan containing products have been pulled
from the shelves in Great Britain.
Triclosan is a polychlorinated biphenyl (PCB) structurally similar to


the weed killer 2,4D. It shows broad spectrum antibiotic activity and is
classed as a pesticide by the EPA. This activity is thought to arise from
the poisoning of a specific microbial enzyme not found in humans. Effect-
iveness is attributed to the layering of a coating in the mouth which is not
washed out.
A main concern is that triclosan generates some chloroform when it comes
in contact with chlorinated tap water. Chloroform is a suspected human car-
cinogen, though it should be noted that it was included as an ingredient in
some cough syrups as late as the 1970's. It has also been suggested that
triclosan may be contaminated with small amounts of dioxin during its
synthesis. Other concerns are the general problem of PCBs in waste water
and buildup of tricloasan in human fatty tissues.
Only a dental professional can reasonably evaluate how major an up to
30% reduction in gingivitis and plaque formation actually is. As a layman,
I'd have to say the benefits don't compensate for the potential risks.
While people with pre-existing oral problems are probably good candidates
for triclosan usage, it probably should not be used by the general public.
The image of 6 billion people washing PCBs down their drain in exchange for
a minor improvement in oral health is not a pleasant one.

Learn more about this author, Neil Wagner.
Contact this writer Click here to send this author comments or questions.


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Triclosan: Uses and effects

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    by Neil Wagner

    Triclosan: Is it for you?

    Triclosan is an active ingredient present in some toothpastes, notably
    Colgate Total. Claims of

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