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How does marijuana treat pain?

by B. Leslie Baird

Created on: September 20, 2009   Last Updated: December 11, 2009

References to the use of marijuana as a medical treatment date back nearly 5000 years. Western medicine began approved use of marijuana in the mid-1800's and continued to do so until 1941 when Congress passed the Marijuana Tax Act that severely limited a physicians' ability to prescribe it. Interestingly enough, the American Medical Association (AMA) was one of the most active organizations against this act.

Medical marijuana use, under a doctors supervision, is legal in thirteen states with actual laws varying by the states. These states are: Alaska, California, Colorado, Hawaii, Maine, Michigan, Montana, Nevada, New Mexico, Oregon, Rhode Island, Vermont and Washington. Each state does have its own set of rules and it is advisable to check them frequently as laws are subject to change at any time. It is important to note that in May 2001 the Supreme Court ruled that federal laws make no exception for distributing or growing marijuana by a third party. Simplified, this means users need to grow their own marijuana for medical use as it is illegal for it to be grown by someone else.

The effects of marijuana on the brain are due to the active ingredient, delta-9 tetrahydrocannabinol or THC. THC acts on cannabinoid receptors on nerve cells and influences the activity of those cells. Cannabinoid receptors are found in many parts of the brain that can influence memory, pleasure, thought, concentration and coordination. These receptors react to the THC to reduce the feeling of pain.

Both anecdotal and scientific research evidence suggests that marijuana provides relief to chronic pain sufferers with a variety of ailments ranging from back pain, migraines, glaucoma, cancer and many more. Research by Vinciqeurra et al. found that 78% of patients tested who were resistant to regular drugs for nausea became symptom free with inhaled cannabis use. There are more than 17,000 papers published that deal with scientific clinical research of the therapeutic value of cannabinoids.

One of the most widely known medical uses for marijuana is in treatment for the side effects of chemotherapy. It is used for the reduction of nausea and vomiting associated with chemotherapy. Another well known use is in the treatment of glaucoma. Many standard treatments have very adverse effects and little positive effect on end stage glaucoma. The use of cannabis lowers the intraocular pressure allowing patients to retain their sight and avoid the painful deterioration that leads to blindness.

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