Where Knowledge Rules

Health & Fitness:

Disease

Get a Widget for this title

How diabetes 'works'

Diabetes is one of America's number one killers and if not properly controlled by diet and, if needed, medication, can cause kidney failure, gangrene of the feet and legs, blindness, coma and death.

Diabetes is a complex metabolic disorder in which insulin production is inadequate or ineffective. The pancreas fails to produce insulin in a response to a rise in blood sugar which occurs when food is eaten and absorbed through the intestinal tract. Insulin and glucagon are two hormones synthesized by the pancreas. Insulin regulates carbohydrate metabolism by removing excess glucose or sugar from the blood and glucagon has the opposite effect as insulin, it increases the blood sugar instead of decreasing it.

The liver secretes glucagon, which raises the blood sugar level by stimulating the breakdown of glycogen, stored carbohydrates in the liver. Glycogen is store in the liver until the blood sugar level drops and then it is reconverted into glucose by the influence of insulin for energy. When insulin is inadequate, glucose builds up in the blood resulting in diabetes.

The cause of diabetes is unknown, but there does seem to be a genetic factor involved that tends to predispose some toward diabetes more than others. Also, a diet that is too high in calories may be a factor and the risk of developing diabetes seems to be about four times greater for a person who is obese. Obesity may cause fat cells to become insensitive to insulin causing the failure of insulin to remove excess sugar from the blood. Removal or injury to the pancreas as well as disorders of other endocrine glands can result in diabetes. Experts believe that being obese plays a larger role in developing diabetes than a diet that is too high in sugar.

There are two types of Diabetes, Diabetes Mellitus and Diabetes Insipidus. Diabetes Insipidus is characterized by excessive urination and is caused by a diseased pituitary gland or its nervous pathways. Diabetes Mellitus is the most common type. There are two types of Diabetes Mellitus, juvenile diabetes (growth-onset) and adult diabetes (maturity-onset). Juvenile diabetes usually effects children between the ages of 0 to 14 and almost always requires insulin. Juvenile diabetes is the most difficult to control. Diabetes occurs in all age groups but the greatest occurrence is in middle aged adults. Adult diabetes occurs in the age group of 40 years and over and approximately 85% of the growth-onset diabetics are obese. Adult diabetes is easier to control


Below are the top articles rated and ranked by Helium members on:

How diabetes 'works'

  • 1 of 6

    by Cheryl Kottke

    Diabetes is one of America's number one killers and if not properly controlled by diet and, if needed, medication, can cause

    read more

  • 2 of 6

    by Louy Castonguay

    What is diabetes?

    Insulin resistant diabetes is all about diet. Better food choices make

    read more

  • 3 of 6

    by Mark Lin

    Diabetes, medically known as diabetes mellitus, is the condition in which the hormone insulin functions abnormally. Insulin

    read more

  • 4 of 6

    by Karen Duthie

    Do you know where your Pancreas is? Or what it does?

    It sits just behind your stomach and it's job is to make insulin. If

    read more

  • 5 of 6

    by Tarek Musslimani

    Diabetes mellitus is an endocrine disorder in which the beta-islet cells of the pancreas secrete deficient amounts of the

    read more

View All Articles on:
How diabetes 'works'

Add your voice

Know something about How diabetes 'works'?
We want to hear your view. Write_penWrite now!

Helium Debate

Cast your vote!

Is Lyme disease becoming an epidemic in North America?

Click for your side.

87038

Featured Partner

Per Scholas

Per Scholas is a non-profit organization dedicated to using technology to improve the lives of people in low-income c...more

What is Helium? | Buy Web Content | Contact Us | Privacy | User agreement | DMCA | User Tools | Help | Community | Helium’s Official Blog | Link to Helium

Helium, Inc.
200 Brickstone Square Andover, MA 01810 USA