by Sudesh Samuel

Created on: January 16, 2009

Timing your medication appropriately can be crucial to the success of any treatment regime whether it be to cure a life-threatening condition or simply to alleviate troublesome symptoms.

When best to take a medication depends on the active ingredient, what product form the medication is in, the nature and severity of the condition to be diagnosed, prevented or treated, as well as individual diet and lifestyle. The detailing that your doctor or pharmacist provides often centers on maximizing the effectiveness and safety of the medication.

Getting as much of the active ingredient to be absorbed into the body can be an important goal of correctly timing your medication. Some medication is better absorbed when taken with meals or specific foods while the absorption of others is inhibited when taken in the same way. Extremely little of an osteoporosis medication like Fosamax (alendronate) already ever gets into the body, let alone reaches the bones, under fasting conditions from a single dose. This medication needs to be taken with plain water and without food or other drink, weekly on the same day in an upright position upon first rising. More than 99% of a single dose will be excreted out of the body under such conditions and if the medication is taken with food or at other times during the day, the amount absorbed can be further reduced by another half or more.

Some medications may be safer to take with food rather than on an empty stomach. In better assuring the long-term safety of a painkiller class of medications known as NSAIDs, it may be advisable to avoid taking the medication aspirin for instance, on an empty stomach and to either take the medication with or after food or together with an antacid.

Active ingredients can require a specific dose and timing strategy to be most effective. This is especially so for different types of antibiotics in treating infections. An antibiotic medication like cloxacillin may require four times a day dosing to maintain effective blood levels in treating a skin infection while ciprofloxacin, an antibiotic of a another class that acts differently, may only require once or twice a day dosing to treat a urinary tract infection.

The product form can play an important role in when and how often a medication is taken. Long-acting, delayed or sustained release preparations can work to release the active ingredients of a medication product differently or consistently throughout a day allowing the medication to be therapeutic despite

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